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Is smoking a contraindication to HRT? The favorable effects of estrogens are not lost in smokers when they are applied transdermally. Women who continue to smoke despite all warnings should therefore only be treated via the transdermal route. Oral contraceptives, but not HRT, are contraindicated in elderly smokers.
How long does it take for HRT to take effect? It usually takes a few weeks before you will feel the initial benefits of HRT and up to three months to feel the full effects. It may also take your body time to get used to HRT. When treatment begins you may experience side effects such as breast tenderness, nausea and leg cramps.
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